Search This Blog

Tuesday, November 27, 2018

New Book: Comments:: Interesting but ironic to confuse plasticity with that of degenerative changes....!!!. 

Book Comments: I posted this recently on my LinkedIn:
https://www.linkedin.com/feed/update/urn:li:activity:6472238430750277632

Plasticity in the Nervous System in General or Brain in particular is mainly used to unravel the capacity of new growth such as neuritic or axonal growth after injury or other types of perturbations, furthermore it refers to new neurons formation such as in the case of Neurogenesis and also refers to behavioral recovery which is another form of neuroplasticity. Plasticity is the counteractive or reactive initiation of constructive growth process within the nervous system, either innate or induced. This process takes place in the nervous system due to an insult, injury or trauma, on the other hand, instead of growth (neuroplasticity) when the injury or trauma leads to pathological changes, it is referred into the field of degenerative changes or Neurodegeneration. Since when Neurodegeneration, a major area of neuroscience by itself mixed up with that of Neuroplasticity??. Is this just a terminology issue or the field itself is being misconstrued???. Do we call now neuronal destructive process as a plasticity too?... 
....Neuroplasticity is restoration and recovery of certain areas of the Nervous systems capacity to heal itself or can be induced to happen via experimental designs!. It will be interesting to look into the works and discussions in this new edition..!!

BookNEUROPLASTICITY and Its Dark Sides: Disorders of the Nervous System

Sunday, October 27, 2013

Spinal Cord Stimulation and Recovery of Movements, is there any Progress?...

Spinal Stimulation Gets Paralyzed Patients Moving

  • A few months after being discharged from the hospital, in May 2011, Shillcox saw a news report announcing that researchers had for the first time enabled a paralyzed person to stand on his own. Neuroscientist Susan Harkema at the University of Louisville, in Kentucky, used electrical stimulation to “awaken” the man’s lower spinal cord, and on the first day of the experiments he stood up, able to support all of his weight with just some minor assistance to stay balanced. The stimulation also enabled the subject, 23-year-old Rob Summers, to voluntarily move his legs in other ways. Later, he regained some control of his bladder, bowel, and sexual functions, even when the electrodes were turned off.
  • The breakthrough, published in The Lancet, shocked doctors who had previously tried electrically stimulating the spinal nerves of experimental animals and people with spinal-cord injuries. In decades of research, they had come nowhere near this level of success. “This had never been shown before—ever,” says GrĂ©goire Courtine, who heads a lab focused on spinal-cord repair at the Swiss Federal Institute of Technology in Lausanne and was not involved with the project. “Rob’s is a pioneer recovery. And what was surprising to me was that his was better than what we’ve seen in rats. It was really exciting for me to see.”

DBS and Lab animal studies, recent report on Paralyzed Rats Gait improvement?

Deep Brain Stimulation Improves Paralyzed Rat's Gait

  • Posted

Wednesday, October 23, 2013

Spinal Stem Cell injection to treat Degenerative Disc disease?..

NeoSpine Performs First Spinal Stem Cell Injection Procedure in Washington
NeoSpine is at the forefront of medicine by utilizing stem cells with the goal to regenerate and thus repair diseased spinal tissue.
http://www.theintelligencer.com/article_f5e96e4d-bc96-57c3-a289-22e4def4e76e.html     
St. Louis, MO (PRWEB) October 22, 2013
 

Two physicians from NeoSpine recently performed an innovative stem cell injection procedure on a patient’s spine to treat back pain caused by degenerative disc disease, the first one in the state of Washington. Dr. Richard Rooney and Dr. Kathy Wang, performed the successful pioneering procedure at Microsurgical Spine Center, the Northwest’s leading ambulatory surgery center located just outside of Seattle, Washington. At the forefront of medicine, stem cells use the body’s own healthy cells with the goal to regenerate to repair diseased spinal tissue.
“With stem cell treatment, bone marrow is extracted from the patient’s pelvis bone and is centrifuged to separate the stem cells from the other bone marrow components. The advanced separation and concentration process was developed by our partner, Celling Biosciences,” explained Dr. Rooney. “The extracted stem cells are injected directly into the patient’s affected discs, and the procedure is image guided for complete accuracy.”

Monday, June 3, 2013

Benefit of Intraoperative IONM and Expenses?...

The risks are minimal but they are real, and when you are not using the advanced technology and knowledge available to assess and safeguard the patients from risks of nerve damage or paralysis, your care is flawed and pretty dangerous, if you can spent 25 thousands for surgery and do not use Neuromonitoring that might cost another thousand or two, and you think that is cost effective, then something wrong with such ideas. Bringing safety inside OR must be the top priority of an operating surgeon (performing surgeon). There are several vascular or neurological complications happen during spine surgical procedures that may not be identified timely if you do not use neuromonitoring techniques, and when you find out after the surgery, it is too late.  
I agree with Professor Fessler, right views when it comes to the benefits and cost effectiveness of IONM. However, totally regard this is yet another Rat and Mice study that is irrelevant to the better care and safe outcome of surgeries, if you do not use IONM then you take the responsibility of a life that might be put into serious risks.................so, it is the surgeon who can make that fine decision at the right time.
But Richard Fessler, MD, professor of Neurological Surgery at Northwestern University Feinberg School of Medicine, Chicago, Illinois, disagreed. In a comment to Medscape Medical News, he called the study "very interesting," with predictable but perhaps irrelevant results.

"If you have one patient where the IOM tells you that you have a problem, and causes you to stop what you are doing and correct that problem and perhaps prevent having a patient who is paralyzed, I would argue that that is cost-effective," he said.
He added that he will not change practice on the basis of the study's findings.

Benefit of Intraoperative IONM and Expenses?...

The risks are minimal but they are real, and when you are not using the advanced technology and knowledge available to assess and safeguar...

CC:attribution

Creative Commons License
NeuroMonitoring by ionmnphy.net is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at www.ionmnphy.net.
Permissions beyond the scope of this license may be available at www.ionmnphy.net.