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Tuesday, November 27, 2018

New Book: Comments:: Interesting but ironic to confuse plasticity with that of degenerative changes....!!!. 

Book Comments: I posted this recently on my LinkedIn:
https://www.linkedin.com/feed/update/urn:li:activity:6472238430750277632

Plasticity in the Nervous System in General or Brain in particular is mainly used to unravel the capacity of new growth such as neuritic or axonal growth after injury or other types of perturbations, furthermore it refers to new neurons formation such as in the case of Neurogenesis and also refers to behavioral recovery which is another form of neuroplasticity. Plasticity is the counteractive or reactive initiation of constructive growth process within the nervous system, either innate or induced. This process takes place in the nervous system due to an insult, injury or trauma, on the other hand, instead of growth (neuroplasticity) when the injury or trauma leads to pathological changes, it is referred into the field of degenerative changes or Neurodegeneration. Since when Neurodegeneration, a major area of neuroscience by itself mixed up with that of Neuroplasticity??. Is this just a terminology issue or the field itself is being misconstrued???. Do we call now neuronal destructive process as a plasticity too?... 
....Neuroplasticity is restoration and recovery of certain areas of the Nervous systems capacity to heal itself or can be induced to happen via experimental designs!. It will be interesting to look into the works and discussions in this new edition..!!

BookNEUROPLASTICITY and Its Dark Sides: Disorders of the Nervous System

Sunday, October 27, 2013

Spinal Cord Stimulation and Recovery of Movements, is there any Progress?...

Spinal Stimulation Gets Paralyzed Patients Moving

  • A few months after being discharged from the hospital, in May 2011, Shillcox saw a news report announcing that researchers had for the first time enabled a paralyzed person to stand on his own. Neuroscientist Susan Harkema at the University of Louisville, in Kentucky, used electrical stimulation to “awaken” the man’s lower spinal cord, and on the first day of the experiments he stood up, able to support all of his weight with just some minor assistance to stay balanced. The stimulation also enabled the subject, 23-year-old Rob Summers, to voluntarily move his legs in other ways. Later, he regained some control of his bladder, bowel, and sexual functions, even when the electrodes were turned off.
  • The breakthrough, published in The Lancet, shocked doctors who had previously tried electrically stimulating the spinal nerves of experimental animals and people with spinal-cord injuries. In decades of research, they had come nowhere near this level of success. “This had never been shown before—ever,” says GrĂ©goire Courtine, who heads a lab focused on spinal-cord repair at the Swiss Federal Institute of Technology in Lausanne and was not involved with the project. “Rob’s is a pioneer recovery. And what was surprising to me was that his was better than what we’ve seen in rats. It was really exciting for me to see.”

DBS and Lab animal studies, recent report on Paralyzed Rats Gait improvement?

Deep Brain Stimulation Improves Paralyzed Rat's Gait

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Benefit of Intraoperative IONM and Expenses?...

The risks are minimal but they are real, and when you are not using the advanced technology and knowledge available to assess and safeguar...

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